Skeletal Muscle Ventricles for Total Heart Replacement
نویسندگان
چکیده
منابع مشابه
Skeletal Muscle Ventricles: a Potential Treatment for Heart Failure
Heart failure continues to cause major morbidity and mortality in the United States and worldwide. As operative techniques and immunosuppression have improved over the last several decades, orthotopic cardiac transplantation has become the preferred alternative for treatment of end-stage heart failure. However, a lack of an adequate supply of donors, the problems of chronic rejection, as well a...
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Reinnervation is needed to rescue muscle when motoneurons die in disease or injury. Embryonic ventral spinal cord cells transplanted into peripheral nerve reinnervate muscle and reduce atrophy, but low motoneuron survival may limit motor unit formation. We tested whether transplantation of a purified population of embryonic motoneurons into peripheral nerve (mean ± SE, 146,458 ± 4,011 motoneuro...
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BACKGROUND Skeletal muscle can be used for cardiac assistance after electrical stimulation over a period of several weeks. This will adapt it to do chronic work with no resulting fatigue. The result of this procedure, however, is a reduction of 80% in muscle power, > 60% in muscle mass, and approximately 85% in contractile speed. To minimize these disadvantages, the following study was done to ...
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Skeletal muscle samples, mainly from the deltoid, were studied morphologically and histochemically in 35 patients with chronic heart block and from nine elderly control subject. The average age of the first group was 67-7 (range 11-94) years. Abnormalities were present in 20 cases, no difference being found between patients with idiopathic and secondary heart block. In 15 samples there was incr...
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Cardiac muscle engineering aims at providing functional myocardium to repair diseased hearts and model cardiac development, physiology, and disease in vitro. Several enabling technologies have been established over the past 10 years to create functional myocardium. Although none of the presently employed technologies yields a perfect match of natural heart muscle, it can be anticipated that hum...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1990
ISSN: 0003-4932
DOI: 10.1097/00000658-199009000-00013